Volume 5, Issue 1, June 2019, Page: 36-41
Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus)
Ameta Primasari, Department of Oral Biology, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
Edikin Raja Sinulingga, Department of Oral Biology, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
Received: Feb. 3, 2019;       Accepted: May 27, 2019;       Published: Jun. 20, 2019
DOI: 10.11648/j.ijhnm.20190501.16      View  560      Downloads  111
Lemongrass is one of the plants that widely used as traditional medicine in Indonesia. Lemongrass contains bioactive substances such as flavonoids, phenolic acids and tannins which act as anti-inflammatory and antioxidants that influence the wound healing process. The aim of this study was to compare the differences in buccal and labial mucosal wound healing, and to see the effect of lemongrass extract on the process of increasing oral mucosal epithelial thickness in white rats. This research is a pure experimental design with a post test-only design with control design. This study used 21 white rats divided into 3 groups where the first group of 100% lemongrass extract, the second group of 50% lemongrass extract, and the third group as the treatment that was not treated. The results of the One-way ANOVA and Post-hoc LSD test on the buccal mucosa showed significant differences with the labial mucosa. There were no significant differences in the buccal section with the second group and the third group p = 0.74 (p <0.05). There were no significant differences in the labial section with the first and second groups, but there were significant differences with the third group p = 0.003 (p <0.05). The effect of lemongrass extract has effectiveness in accelerating healing of oral mucosal wounds in white rats. There was also an increase in the thickness of the oral mucosal epithelium after administration of lemongrass extract with concentrations of 100% and 50%. Based on the research that has been done it can be concluded that healing wounds of the buccal mucosa heal faster than labial mucosal wounds because the buccal part contains saliva which has an important role in the wound healing process.
Lemongrass Extract, Wound Healing, Wound Length, Thickness of the Epithelium, Oral Mucosa, White Mice
To cite this article
Ameta Primasari, Edikin Raja Sinulingga, Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus), International Journal of Homeopathy & Natural Medicines. Vol. 5, No. 1, 2019, pp. 36-41. doi: 10.11648/j.ijhnm.20190501.16
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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